The manufacturer of hydrocodone bitartrate extended-release tablets states that dosage of this formulation should be reduced by 50% in patients with moderate or severe renal impairment (including end-stage renal disease); the manufacturer states that the extended-release tablets may be used without dosage adjustment in patients with mild renal ...
See also Warning section. Before taking this medication, tell your doctor or pharmacist if you are allergic to it; or to other opioids (such as benzhydrocodone, hydromorphone, morphine, codeine); or if you have any other allergies.
Hydrocodone is a potent analgesic commonly prescribed for moderate-to-severe pain management in postoperative settings, trauma patients, and individuals with cancer. When combined with acetaminophen, hydrocodone demonstrates increased efficacy without significantly altering the adverse effect profile, as evidenced by randomized studies. This combination is …
Hydrocodone (such as Vicodin®, Norco®) Oxycodone (such as OxyContin®, Percocet®) Morphine (such as MS Contin®, Kadian®) Prescription opioids for pain management. Prescription opioids (opioid therapy) can be used to treat acute-to-chronic pain and are often prescribed following surgery or injury, or for health conditions such as cancer.
DESCRIPTION Hydrocodone bitartrate and acetaminophen is supplied in tablet form for oral administration. Hydrocodone bitartrate is an opioid analgesic and antitussive and occurs as fine, white crystals or as a crystalline powder. It is affected by light. The chemical name is: 4,5a- Epoxy-3-methoxy-17-methylmorphinan- 6-one tartrate (1:1) hydrate (2:5).
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Designated as a Schedule 2 substance by the U.S. Drug Enforcement Administration (DEA), hydrocodone comes from a class of drugs known as opioids. 2 Schedule 2 drugs have valid medical use, but also have the potential for misuse and a high risk of addiction and harmful effects when misused. In addition to being classified as an opioid analgesic to relieve pain, …
Hydromorphone. Mechanism of Action: Hydrogenated ketone analogue of morphine that can be formed by the N-demethylation of hydrocodone.Binds to mu-opioid receptors in the central nervous system. IV – Initial Effect - 5 minutes, Peak Effect - 8-20 min, Duration 1-2 hours . Oral– Initial Effect 30 minutes; Duration 3-4 hours. Starting Dose – IV – 0.2-0.6mg every 2-3 hours ; …
Find patient medical information for Hydrocodone HD oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings.
Hydrocodone/ 0.05 - 0.2 mg/kg/dose Q3-4 acetaminophen Bisacodyl(Elixir: 0.5 mg hydrocodone/33.4 mg acetaminophen per mL) (PO/PR) >3(Tablet: 5 mg hydrocodone/325 mg acetaminophen) Hydromorphone (PO) 0.03 - 0.08 mg/kg/dose Q4-6 (IV) 0.01 mg/kg/dose (IV) 5 Q4-6 Ibuprofen Clonidine**5 - 10 mg/kg/dose (Max: 40mg/kg/day, 400 mg/dose) Q6-8
Duragesic [package insert]. Titusville (NJ): Janssen Pharmaceuticals, Inc; 2012. DailyMed Monograph; Skaer TL. Practice guidelines for transdermal opioids in malignant pain.
Parchem supplies Hydrocodone Bitartrate and a range of specialty chemicals worldwide
Hydrocodone is a semi-synthetic opioid medication that is classified as a schedule II drug. This medication is approved by the U.S. Food and Drug Administration (FDA) and used for pain management. Hydrocodone is primarily used to treat severe chronic pain that requires opioid analgesia and is not effectively treated by nonopioid alternatives. Hydrocodone is used in …
Hydrocodone is habit-forming and potentially abusable. The combination of acetaminophen and hydrocodone should only be used short-term at the lowest effective dose when other nonopioid analgesics are not effective. Legitimate supplies of products containing hydrocodone may be sought out by drug seekers. Hydrocodone is one of the most abused ...
Drugs provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Data sources include Micromedex (updated 2 Dec 2024), Cerner Multum™ (updated 3 Feb 2025), ASHP …
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Find patient medical information for Vicodin HP oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings.
Purpose of Oral Morphine Equivalence (OME) calculations. OME calculations help identify opioid tolerance in individual patients. The FDA defines an opioid-tolerant patient as receiving for 1 week or longer at least 60 mg oral morphine/day or an equianalgesic dose of another opioid.
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Vicodin contains a combination of acetaminophen and hydrocodone. Hydrocodone is an opioid pain medication. An opioid is sometimes called a narcotic. Acetaminophen is a less potent pain reliever that increases …
What is Hydrocodone? Hydrocodone is a powerful narcotic pain medication used to treat moderate to severe pain. It belongs to a class of drugs known as semi-synthetic opioids, which means it is derived from codeine, a naturally occurring substance found in the opium poppy.
Analgesic products containing hydrocodone in combination with the anti-inflammatory drug ibuprofen (hydrocodone bitartrate/ibuprofen 2.5–7.5 mg/200 mg) to be taken by oral administration and a long-acting formulation of …
Hydrocodone is a hydrogenated ketone derivative of codeine. Hydrocodone bitartrate occurs as fine, white crystals or crystalline powder and is soluble in water and slightly soluble in alcohol. Hydrocodone polistirex consists of hydrocodone with a cation-exchange resin copolymer complex of sulfonated styrene-divinylbenzene.
Initiation of CYP3A4 inhibitors (or discontinuation of CYP3A4 inducers) can result in a fatal overdose of hydrocodone from hydrocodone ER Contains acetaminophen Hepatotoxicity may occur with acetaminophen doses that exceed 4 g/day; take into account all acetaminophen-containing products the patient is taking, including PRN doses and OTC products
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Hydrocodone is controlled in schedule II of the Controlled Substances Act. (Correction): Previously, it was reported that, within the 2016 NSDUH, 11.5 million people in the U.S. population, aged 12 and older, misused hydrocodone in the past year compared to 12.5 million in 2015, a significant
Hydrocodone is a semisynthetic, moderately potent, orally available opioid that, in combination with acetaminophen, is widely used for treatment of acute or chronic pain, and in combination with antihistamines or anticholinergics used to treat cough. Hydrocodone by itself has not been linked to serum enzyme elevations during therapy or to clinically apparent liver injury, …
Hydrocodone bitartrate and acetaminophen is supplied in tablet form for oral administration. Hydrocodone bitartrate is an opioid analgesic and antitussive and occurs as fine, white crystals or as a crystalline powder. It is affected by light. The chemical name is 4,5α-Epoxy-3-methoxy-17-methylmorphinan-6-one tartrate (1:1) hydrate (2:5).